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Click on image to open expanded view Item No. 28826

Advantage Multi Topical for Dogs Rx

By Advantage
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Product Description
Advantage Multi for dogs provides broad-spectrum parasite protection in a convenient monthly application. It prevents heartworm disease, kills fleas, and treats and control roundworms, hookworms, whipworms and sarcoptic mange - all in one easy-to-use topical application.
What is Advantage Multi Topical for Dogs?
Advantage Multi is a monthly topical solution for dogs to prevent heartworm disease. It kills adult fleas, is indicated for the treatment of flea infestations, as well as the treatment and control of intestinal parasite infections.
Who is Advantage Multi Topical for Dogs for?
Advantage Multi for dogs and puppies that are at least 7+ weeks old and weigh 3+ lbs.
Why use Advantage Multi Topical for Dogs?
- Once a month easy to use protection
- All in one treatment for fleas, parasites, and heartworm prevention.
How does Advantage Multi Topical for Dogs work?
Advantage Multi® for Dogs (10% imidacloprid + 2.5% moxidectin) is a colorless to yellow ready-to-use solution packaged in single dose applicator tubes for topical treatment of dogs. The formulation and dosage schedule are designed to provide a minimum of 4.5 mg/lb (10 mg/kg) imidacloprid and 1.1 mg/lb (2.5 mg/kg) moxidectin based on body weight.
Active Ingredients(s):
10% imidacloprid + 2.5% moxidectin
How is Advantage Multi Topical for Dogs sold?
What are the side effects of Advantage Multi Topical for Dogs?
Adverse events reported in dogs topically treated with imidacloprid + moxidectin for dogs included: vomiting, diarrhea, bloody diarrhea, salivation, poor appetite, lethargy, weakness, restlessness, agitation, disorientation, ataxia, muscle tremors, seizures, panting, labored breathing, acute pulmonary edema, hives, rash, swollen face and ears, pruritus, erythema, alopecia, hot spots, local discomfort, and discoloration of the hair at the application site. Accidental oral ingestion in dogs caused salivation, vomiting, muscle tremor, seizures, mydriasis, ataxia, lethargy, disorientation, agitation, and poor appetite. Adverse reactions reported in cats treated topically with imidacloprid + moxidectin for dogs included application site and skin reactions, vomiting, lethargy, agitation, and neurologic signs
What special precautions are there?
For the first 30 minutes after application: Ensure that dogs cannot lick the product from application sites on themselves or other treated dogs, and Separate treated dogs from one another and from other pets to reduce the risk of accidental ingestion. Ingestion of this product by dogs may cause serious adverse reactions including depression, salivation, dilated pupils, incoordination, panting, and generalized muscle tremors. In avermectin sensitive dogs,a the signs may be more severe and may include coma and death.
What to do if overdose?
Contact your nearest animal hospital
How can I store Advantage Multi Topical for Dogs?
Store at temperatures between 4°C (39°F) and 25°C (77°F), avoiding excess heat or cold.
Helpful Tips:
Do not use this product (containing 2.5% moxidectin) on cats.

The recommended minimum dose is 4.5 mg/lb (10 mg/kg) imidacloprid and 1.1 mg/lb (2.5 mg/kg) moxidectin, once a month, by topical administration. Do not apply to irritated skin.

1. Remove one dose applicator tube (tube) from the package. As specified in the following table, administer the entire contents of the Advantage Multi® for Dogs tube that correctly corresponds with the body weight of the dog.

Dog (lbs.)

Advantage Multi For Dogs

Volume (mL)

Imidacloprid (mg)

Moxidectin (mg)

3 - 9

Advantage Multi 9




9.1 - 20

Advantage Multi 20




20.1 - 55

Advantage Multi 55




55.1 - 88

Advantage Multi 88




88.1 - 110*

Advantage Multi 110





* Dogs over 110 lbs. should be treated with the appropriate combination of Advantage Multi for Dogs tubes.
Main Ingredients
(imidacloprid + moxidectin)