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Frontline Plus For Dogs

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California Residents: Prop. 65 Warning

This product may contain chemicals known to the State of California to cause cancer, birth defects, or other reproductive harm. For more information, go to www.P65Warnings.ca.gov

Product Description
Treat your pet with FRONTLINE Plus, trusted by vets for over 20 years, waterproof, fast-acting kills fleas, flea eggs, lice, and ticks. Designed for use only with dogs eight weeks or older, this long-lasting treatment is made for dogs weighing between 5 and 132 pounds. Made with two active ingredients, fipronil and (S)-methoprene, this treatment stops infestations and prevents new ones. It kills ticks that may transmit diseases, like Lyme disease and Rocky Mountain spotted fever, and aids in the control of sarcoptic mite mange infestations. One easy topical application works for a full 30 days.
What is Frontline Plus For Dogs?
FRONTLINE PLUS FOR DOGS is a monthly topical treatment that provides fast, effective and convenient treatment and control of fleas, ticks and chewing lice for dogs and puppies.
Who is Frontline Plus For Dogs for?
Dogs and Puppies (8 weeks of age and older)
Why use Frontline Plus For Dogs?
Provides fast-acting, long-lasting flea and tick protection for dogs 8 weeks or older and weighing 5 lbs or more. Kills adult fleas, ticks, chewing lice, mites, and flea eggs and larvae. Waterproof 24 hours after application. Easy to apply for once a month for lasting protection. For best results, apply every month.

Safe for use on lactating, pregnant, and breeding females
Helps control infestations of sarcoptic mange
Quickly eradicates chewing lice infestations
Kills potential Lyme disease-carrying deer ticks at all stages (lone star, American dog, and brown dog ticks)
Kills fleas, which could cause flea allergy dermatitis
How does Frontline Plus For Dogs work?
FRONTLINE® PLUS FOR DOGS contains fipronil and the insect growth regulator (IGR) (S)-methoprene. FRONTLINE® PLUS effectively targets all stages of fleas. Fipronil collects in the oils of the skin and hair follicles, and continues to be released from hair follicles onto the skin and coat, resulting in long-lasting activity against fleas, ticks and chewing lice.
Boehringer Ingelheim
Active Ingredients(s):
fipronil, (S)-methoprene
How is Frontline Plus For Dogs sold?
FRONTLINE® PLUS FOR DOGS is available Over the Counter (OTC) in 3, 6, and 12 month supplies.
Boxes are color coordinated according to your dog's weight.
  • Orange: 5 - 22 lbs. (Small Dogs)
  • Blue: 23 -44 lbs. (Medium Dogs)
  • Purple: 45-88 lbs. (Large Dogs)
  • Red: 89 - 132 lbs. (Extra Large Dogs)
What are the side effects of Frontline Plus For Dogs?
Potential side effects include: Loss of appetite, diarrhea, excessive salivation, irritation at the application site, itching, swelling
What special precautions are there?
  • Do not store or use near open flame or heat. This product is combustible.
  • Speak with your veterinarian before use on aged, debilitated, or medicated pets. For 24-hour-a-day assistance, call 1-800-660-1842.
  • Some medications may interact with pesticides.
  • Contact your veterinarian prior to repeat treatment if your pet exhibits an unusual reaction to their initial application.
  • Irritation site pain is the most common side effect. If symptoms persist or worsen within a few days following application, contact your veterinarian.
  • Rarely, individual sensitivities can occur following pesticide use.
  • Do not administer to puppies under the age of 8 weeks.
  • Intended only for external use.
  • Do not allow contact with clothing, eyes, or skin.
  • Thoroughly wash hands after handling. If skin contact occurs, wash repeatedly with soap and water. Contact a doctor if irritation continues.
  • Harmful if swallowed. If accidentally swallowed, contact a doctor or poison control center immediately to obtain advice about treatment. Ensure that the affected person sips water if they are able to swallow. Do not induce vomiting unless instructed by a doctor or poison control center. Do not give an unconscious person anything by mouth.
  • Causes eye irritation. If contact with the eyes occurs, flush with copious amounts of water and contact a doctor if the irritation continues.
What to do if overdose?
Contact your nearest animal hospital.
How can I store Frontline Plus For Dogs?
Only store unused product in original container.
Keep out of reach of children and animals.
Helpful Tips:
The entire container should be applied to the same area on your dog (between the shoulder blades). Do not apply on top of the hair. Instead, part the hair and apply to the skin.
Apply to dogs or puppies (8 weeks or older) as follows:
Remove applicator from child-resistant package. Hold applicator upright and snap applicator tip away from face and body. Place applicator tip through animal’s hair to the skin level between the shoulder blades. Squeeze applicator, applying entire contents in a single spot to the animal’s skin. Avoid superficial application to the animal’s hair. Only one applicator per treatment is needed.
FRONTLINE® PLUS aids in the control of sarcoptic mange infestations. Multiple monthly treatments are recommended for the elimination of mites.
When used monthly, FRONTLINE® PLUS FOR DOGS completely breaks the flea life cycle and controls tick and chewing lice infestations. Research demonstrates that
FRONTLINE® PLUS kills adult fleas, flea eggs, and flea larvae for up to three months. FRONTLINE® PLUS also prevents development of all flea stages for up to three months.
Although FRONTLINE® PLUS can control fleas for up to three months, if there is a high risk of reinfestation or if the pet has fleas which may cause flea allergy dermatitis, a once monthly application may be needed. FRONTLINE® PLUS kills ticks for at least one month. A once monthly application is recommended where tick control is needed.
FRONTLINE® PLUS kills chewing lice for at least one month.
A once monthly application is recommended where chewing lice control is needed. FRONTLINE® PLUS FOR DOGS remains effective even after bathing, water immersion, or exposure to sunlight. Avoid contact with treated area until dry. Do not reapply FRONTLINE® PLUS for 30 days.
Main Ingredients
FOR DOGS & PUPPIES 8 weeks or older
Convenient spot treatment for fast-acting, long-lasting control of fleas, ticks and chewing lice.
fipronil: 9.8%
(S)-methoprene 8.8%
TOTAL 100.0%