ToDAY (cephapirin sodium) for Intramammary Infusion should be used at the first signs of inflammation or at the first indication of any alteration in the milk. Treatment is indicated immediately upon determining, by C.M.T. or other tests, that the leukocyte count is elevated, or that a susceptible pathogen has been cultured from the milk. ToDAY (cephapirin sodium) is a cephalosporin which possesses a wide range of antimicrobial activity against gram-positive and gram-negative organisms. It is derived biosynthetically from 7-aminocephalosporanic acid. Each 10 mL disposable syringe contains 200 mg of cephapirin activity in a stable peanut oil gel.

Use as directed by your veterinarian. DOSAGE AND DIRECTIONS FOR USE: Infuse the entire contents of one syringe (10 mL) into each infected quarter immediately after the quarter has been completely milked out. Repeat once only in 12 hours. If definite improvement is not noted within 48 hours after treatment, the causal organism should be further investigated. Consult your veterinarian. Milk out udder completely. Wash the udder and teats thoroughly with warm water containing a suitable dairy antiseptic and dry, preferably using individual paper towels. Carefully scrub the teat end and orifice with 70% alcohol, using a separate swab for each teat. Allow to dry. ToDAY (cephapirin sodium) is packaged with the Opti-Sert® Protective Cap. For partial insertion: Twist off upper portion of the Opti-Sert Protective Cap to expose 3–4 mm of the syringe tip. For full insertion: Remove protective cap to expose the full length of the syringe tip. Insert syringe tip into the teat canal and expel the entire contents of one syringe into each infected quarter. Withdraw the syringe and gently massage the quarter to distribute the suspension into the milk cistern. Do not milk out for 12 hours. Do not infuse contents of the mastitis syringe into the teat canal if the Opti-Sert Protective Cap is broken or damaged. Reinfection – The use of antibiotics, however effective, for the treatment of mastitis will not significantly reduce the incidence of this disease in the herd unless their use is fortified by good herd management, and sanitary and mechanical safety measures are practiced to prevent reinfection.

Cephapirin Sodium