Revolution Plus for Cats is indicated for the prevention of heartworm disease caused by Dirofilaria immitis. It kills adult fleas (Ctenocephalides felis) and is indicated for the treatment and prevention of flea infestations, the treatment and control of tick infestations with Ixodes scapularis (black-legged tick), Amblyomma maculatum (Gulf Coast tick) and Dermacentor variabilis (American dog tick), the treatment and control of ear mite (Otodectes cynotis) infestations, and the treatment and control of roundworm (Toxocara cati) and intestinal hookworm (Ancylostoma tubaeforme) infections for one month in cats and kittens 8 weeks and older, and weighing 2.8 pounds or greater.
What is Revolution Plus for Cats?
Revolution Plus for Cats is indicated for the prevention of heartworm disease caused by Dirofilaria immitis. It kills adult fleas (Ctenocephalides felis) and is indicated for the treatment and prevention of flea infestations, the treatment and control of tick infestations with Ixodes scapularis (black-legged tick), Amblyomma maculatum (Gulf Coast tick) and Dermacentor variabilis (American dog tick), the treatment and control of ear mite (Otodectes cynotis) infestations, and the treatment and control of roundworm (Toxocara cati) and intestinal hookworm (Ancylostoma tubaeforme) infections for one month.
Who is Revolution Plus for Cats for?
Cats and Kittens 8 weeks or older and weighing 2.8 lbs or greater
Why use Revolution Plus for Cats?
-Provides 6 in 1 protection against Heartworms, Fleas, Ticks, Ear Mites, Roundworms and Hookworms
-Easy to use topical spot on
-Provides 1 month of protection per application
How does Revolution Plus for Cats work?
Revolution Plus contains two active ingredients selamectin and sarolaner. Selamactin paralyzes and/or kills a wide range of invertebrate parasites through interference with their chloride channel conductance causing disruption of normal transmission. This inhibits the electrical activity of nerve cells in nematodes and muscle cells in arthropods leading to their paralysis and/or death. Sarolaner is an acaricide and insecticide. Sarolaner blocks GABA and glutumate gated chloride channels in the nervous system of insects and acarines thus resulting in increased nerve stimulation and death of the target parasite.
Selamectin and Sarolaner
How is Revolution Plus for Cats sold?
Available in 3 or 6 month supply depending on your cats weight as follows :
2.8 to 5.5 lbs GOLD (3 month or 6 month supply)
5.6 to 11 lbs ORANGE (3 month or 6 month supply)
11.1 to 22 lbs GREEN (3 month or 6 month supply)
What are the side effects of Revolution Plus for Cats?
Possible side effects of Revolution Plus may include lethargy, diarrhea, emesis, eczema, skin lesions, anorexia, pruritus, conjunctivitis, sneezing, administration site hair changes, or administration site lesions. Sarolaner, one of the ingredients in Revolution Plus is a member of the isoxazoline class. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. Neurologic adverse reactions have been reported in cats receiving isoxazoline class drugs, even in cats without a history of neurologic disorders. Use with caution in cats with a history of neurologic disorders.
What special precautions are there?
Keep away from children and animals. The safe use of Revolution Plus has not been evaluated in kittens less than 8 weeks of age or in breeding, pregnant, or lactating cats. Revolution Plus may be irritating to the skin and eyes. Use caution when applying and wash hands with soap and water after applying. Flammable - Keep away from heat, sparks, open flames or other sources of ignition.
Contact your nearest emergency animal hospital
How can I store Revolution Plus for Cats?
Store at or below 30*C (86*F)
Use as directed by your Veterinarian.
The recommended minimum dosage is 2.7 mg selamactin per pound (6 mg/kg) of body weight and 0.45 mg sarolaner per pond (1 mg/kg) of body weight.
A veterinarian or veterinary technician should demonstrate or instruct the pet owner regarding the appropriate technique for applying REVOLUTION PLUS topically to cats and kittens prior to first use.
Firmly press the cap down to puncture the seal on the REVOLUTION PLUS tube; a clicking sound will confirm that the cap has successfully punctured the seal. Remove the cap and check to ensure that the tip of the tube is open. To administer the product, part the hair on the back of the animal at the base of the neck in front of the shoulder blades until the skin is visible. Place the tip of the tube on the skin and squeeze the tube 3 or 4 times to empty its entire contents directly on the skin in one spot. Keeping the tube squeezed, drag it away from the liquid and lift to remove. Check the tube to ensure that it is empty.
Do not massage the product into the skin. Due to alcohol content, do not apply to broken skin. Avoid contact between the product and fingers. Do not apply when the hair coat is wet. Stiff hair, clumping of hair, hair discoloration, or a slight powdery residue may be observed at the treatment site in some cats. These effects are temporary and do not affect the safety or effectiveness of the product. Discard empty tubes in yor ordinary household refuse.
The effectiveness of REVOLUTION PLUS against D. immitis after bathing has not been evaluated. Bathing or shampooing the cat 24 hours after treatment does not reduce the effectiveness of topical selamectin, one f the ingredients of REVOLUTION PLUS, against D. immitis.
Flea Treatment and Prevention: For the treatment and prevention of flea infestations, REVOLUTION PLUS may begin at anytime of year. REVOLUTION PLUS shold be administered year-round at monthly intervals or begin at least one month before fleas become active. If a cat is already infested with fleas when the first dose of REVOLUTION PLUS is administered, adult fleas on the animal are killed before they can lay eggs. However, an environmental infestation may persist for a short time after beginning treatment with REVOLUTION PLUS because of the development of adult fleas from eggs that were laid prior to the initiation of treatment.
Tick Treatment and Control: For the treatment and control of infestations with Ixodes scapularis, Amblyomma maculatum and Dermacentor variabilus, REVOLUTION PLUS may begin at any time of year. REVOLUTION PLUS should be administered year-round at monthly intervals or begin at least one month befor ethe ticks become active.
Heartworm Prevention: For the prevention of heartworm disease, REVOLUTION PLUS must be administered on a monthly basis. REVOLUTION PLUS should be administered year-round or at least within one month after the animal's first exposure to mosquitoes and monthly thereafter until the end of the mosquito season. The final dose must be given within one month after the last exposure to mosquitoes. If a dose missed and a monthly interval between dosing is exceeded then immediate administration of REVOLUTION PLUS and resumption of monthly dosing will minimize the opportunity for the development of adult heartworms. When replacing another monthly heartworm preventive product in a heartworm disease prevention program, the first dose of REVOLUTION PLUS must be given within a month of the last dose of the former medication.
Selamectin, one of the active ingredients in REVOLUTION PLUS, is a macrocryclic lactone compound. These compounds effectively prevent the development of adult heartworms when administered to cats within one month of exposure to infective (L3) Dirofilaria immitis larvae. This product effectively eliminates the tissue stage of heartworm larvae for a month after infection. Cats with unknown heartworm history that test negative prior to the initiation of REVOLUTION PLUS may be harboring pre-patent infections at the time REVOLUTION PLUS was started. Testing such animals 3-4 months after initiation of REVOLUTION PLUS would be necessary to confirm their negative heartworm status.
At the discretion of the veterinarian, cats > 6 months of age may be tested to determine the presence of existing heartworm infections before beginning treatment with REVOLUTION PLUS. Cats already infected with adult heartworms can be given REVOLUTION PLUS monthly to prevent further infections.
Ear Mite Treatment and Control: For the treatment of ear mite (Otodectes cynotis) infestations, REVOLUTION PLUS should be administered once as a single topical dose. Do not administer into the ear canal. Monthly use of REVOLUTION PLUS will control any subsequent ear mite infestations. Cleansing of the infested ears is recommended to remove debris.
Nematode Treatment and Control: For the treatment of roundworm (Toxocara cati) and intestinal hookworm (ancylostoma tubaeforme) infections, REVOLUTION PLUS should be applied once as a single topical dose. Monthly use of REVOLUTION PLUS will control any subsequent roundworm and intestinal hookworm infections.
Active Ingredients in Revolution Plus for Cats : Selamectin and Sarolaner
Body Weight (lb) / Tube Cap Color / Tube Colume (mL) / Selamectin (mg/tube) / Sarolaner (mg/tube)
2.8-5.5 Gold 0.25 15 2.5
5.6-11 Orange 0.5 30 5
11.1-22* Green 1 60 10