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Click on image to open expanded view Item No. 49602

Incurin (Estriol) 1 mg, 30 Tablets Rx

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Product Description
Incurin uses short-acting estrogen to treats spayed female dogs with urinary incontinence. An alternative to phenylpropanolamine medications like Proin, this safe once-daily tablet reduces and often eliminates the leakage and accidents resulting from urinary incontinence.
What is Incurin (Estriol) 1 mg, 30 Tablets?
Incurin treats urinary incontinence in spayed female dogs with short acting estrogen that counteracts the loss suffered by dogs with urinary issues. This significantly reduces and most times eliminates the leakage and accidents resulting from urinary incontinence. The goal is to give the minimum dose that controls your dog’s symptoms. If the initial dose is working after this time period, try to reduce the dose to ½ tablet per day, then ½ tablet on alternate days.
Who is Incurin (Estriol) 1 mg, 30 Tablets for?
Incurin is used to treat female spayed dogs.
Why use Incurin (Estriol) 1 mg, 30 Tablets?
To restore urinary incontinence in spayed dogs, especially older females
How does Incurin (Estriol) 1 mg, 30 Tablets work?
It uses short-acting estrogen to restore sphincter muscle tone
Merck Animal Health
Active Ingredients(s):
Tablets contain 1 mg of estriol in each tablet
How is Incurin (Estriol) 1 mg, 30 Tablets sold?
Incurin is sold in foil-sealed blister packs of 30 single-scored tablets.
What are the side effects of Incurin (Estriol) 1 mg, 30 Tablets?
The most common side effects of estriol were reduced appetite and vomiting. Appetite reduction was experienced in about 13% of dogs and vomiting in about 10%. Reducing the dose generally controls these issues.
What special precautions are there?
Some estrogens have been associated with bone marrow changes and an increased risk of mammary tumors. However, target animal safety study results and foreign post-market pharmacovigilance data for INCURIN™ Tablets have shown that estriol-treated dogs are at low risk for developing these conditions. FOR ANIMAL USE ONLY - NOT FOR HUMAN CONSUMPTION KEEP OUT OF REACH OF CHILDREN
What to do if overdose?
Contact your vet or the nearest Animal hospital immediately.
How can I store Incurin (Estriol) 1 mg, 30 Tablets?
Store at or below 25°C (77°F) with excursions permitted to 40°C (104°F)
Helpful Tips:
Incurin is usually an alternative treatment for incontinence when phenylpropanolamine (PPA, Proin) is no longer affective but can be the first choice in therapy because of its effectiveness.
The dose of INCURIN® Tablets is not dependent upon body weight. All dogs should receive an initial dose of 2 mg INCURIN® Tablets (2 tablets) orally once per day for a minimum of 14 days. After urinary incontinence is controlled, the lowest effective daily dose of INCURIN® Tablets should be determined by decreasing the dose in a step-wise manner from 2 mg once daily (2 tablets) to 1 mg once daily (1 tablet), then 0.5 mg once daily (1/2 tablet) depending upon the response of the individual dog. There should be a minimum of 7 days between each dose adjustment. After the lowest daily dose that controls urinary incontinence is identified, the dose may be decreased further by administering once every two days. Dogs should not receive more than 2 mg INCURIN® Tablets per day (2 tablets). If the dog does not respond to 2 mg of INCURIN™ Tablets per day, the diagnosis should be re-assessed.
Main Ingredients
Incurin contains 1 mg of estriol in each tablet